| Schedule of Reconciliation to the Consolidated Net Loss | 
A reconciliation to the
consolidated net loss for the years ended December 31, 2024, and 2023 is included at the bottom of the table below.
  
    |   | 
  | 
    As of December 31, | 
  | 
 
  
    |   | 
  | 
    2024 | 
  | 
  | 
    2023 | 
  | 
 
  
    | Significant segment expenses | 
  | 
      | 
  | 
  | 
      | 
  | 
 
  
    | General and administrative (1) | 
  | 
    $ | 
5,786,293 | 
  | 
  | 
    $ | 
6,306,707 | 
  | 
 
  
    | Pre-clinical research (1) | 
  | 
      | 
1,479,896 | 
  | 
  | 
      | 
3,584,483 | 
  | 
 
  
    | CMC (1) | 
  | 
      | 
1,463,530 | 
  | 
  | 
      | 
2,490,729 | 
  | 
 
  
    | Clinical development (1) | 
  | 
      | 
4,097,521 | 
  | 
  | 
      | 
1,652,808 | 
  | 
 
  
    | License milestone payments | 
  | 
      | 
-  | 
  | 
  | 
      | 
250,000 | 
  | 
 
  
    | Depreciation and amortization | 
  | 
      | 
649,029 | 
  | 
  | 
      | 
648,454 | 
  | 
 
  
    | Share based compensation expense | 
  | 
      | 
773,693 | 
  | 
  | 
      | 
592,269 | 
  | 
 
  
    | Other segment items (2) | 
  | 
      | 
-  | 
  | 
  | 
      | 
453,911 | 
  | 
 
  
    | Total operating and segment expenses | 
  | 
    $ | 
14,249,962 | 
  | 
  | 
    $ | 
15,979,361 | 
  | 
 
  
    |   | 
  | 
      | 
  | 
  | 
  | 
      | 
  | 
  | 
 
  
    | Reconciliation of net loss | 
  | 
      | 
  | 
  | 
  | 
      | 
  | 
  | 
 
  
    | Change in fair value of warrant liabilities | 
  | 
      | 
77,806 | 
  | 
  | 
      | 
(56,245 | 
) | 
 
  
    | Interest and dividends, net | 
  | 
      | 
(423,184 | 
) | 
  | 
      | 
(415,368 | 
) | 
 
  
    | Adjustments and reconciling items (3) | 
  | 
      | 
-  | 
  | 
  | 
      | 
453,910 | 
  | 
 
  
    | Segment and consolidated net loss | 
  | 
    $ | 
13,904,584 | 
  | 
  | 
    $ | 
15,961,658 | 
  | 
 
   
   
 | 
(1) | 
includes personnel costs and excludes share-based compensation
expense | 
  
 | 
(2) | 
includes litigation settlements, loss from sale of assets, and
loss on asset write offs | 
  
 | 
(3) | 
includes net loss from discontinued operations | 
  
 |